AN UNBIASED VIEW OF BLOCK PAIN RECEPTORS WITH PROLEVIATE

The activation of CB1 and CB2 inhibits the development of intracellular cAMP, therefore leading to an incredible reduction in the excitatory influence within the neurons [88,89]. On top of that, the activation of CB2 can more avoid the mast mobile degranulation and the release of professional-inflammatory mediators, producing the reduction in pain